All dyes, natural or synthetic, are chemicals, but the term “chemical dyes” refers to those synthesized in the laboratory. Aniline is a chemical substance derived from coal-tar. Discovered in 1856, it was the first synthetic dyestuff. The applications of a number of dyes produced from aniline changed the world’s dye industry. It is sometimes used as a general term for synthetic or chemical dyes. This are made of non-natural substances.